Personal Genomics is like the internet in the 90s

Turnaround time is slow
Sequencing requires expertise and resources
Hardware is expensive
Use cases are limited
THE SOLUTION
A device that anyone can use, anywhere, opening up access to sequencing technology anywhere around the world. We start this evolution with the 454 Bio.
Get StartedLow cost Device
Affordable for labs and research institutions of any size.
Easy to Use Kits
Customizable pods available for subsequent runs.
The 454 Bio

Results without Expertise
Simply load and start the machine to get results.
Seamless Data Transfer
Easy to use data tools and sync with other devices.
What Are the Advantages of Decentralized, On-Site Sequencing Compared to Sequencing at a Centralized, Remote Laboratory?
Immediate results
Results available in less than 1 hour VS days/weeks
Frequent Testing
Makes frequent at-home testing possible
Distributed
Sequence anywhere and build network effects
Ultimate Privacy
Sample stays with the patient/consumer
Our Team and Founding Advisors

Jonathan Rothberg, PhD
Co-founder



Michael Metzker, PhD
Co-founder


Antoine Van Oijen, PhD
Single Molecule Biophysics, advisor


Andrew Griffith, PhD
Droplet Microfluidics, advisor

454 Bio is The 9th Startup In
the 4Catalyzer Family
About Us
2000-2011
First Next-Gen DNA Sequencing
- First semiconductor chip for DNA sequencing
- Awarded Presedintial Medal of Technology & Innovation in 2016
2011-2022
4Catalyzer
- First ultrasound on chip
- First portable MRI
- First semiconductor chip for single moledule proteomics and protein sequencing
- 8 C Corps, 750+ employees
Today
Today
- Quantum Si ($QSI) on NASDAQ
- Hyperfine + Liminal ($HYPR) on NASDAQ
- Butterfly Network ($BFLY) on NYSE
Careers
At 454 Bio our mission is to push forward scientific discovery and spread access to diagnostic technology. If you'd like to join our team, we look forward to hearing from you.
View Open Positions