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Polymerase competition
Tuesday, January 23, 2024 in Blog
454 Bio have opened a competition with a prize of $200,000.00 to evolve a DNA polymerase optimized to use Lightning Terminators™️ while not incorporating their hydroxymethyl cleavage products with a minimum 1000:1 ratio. See below for the full …
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454 Bio Unveils Revolutionary Open Source DNA Sequencing Platform
Tuesday, January 23, 2024 in Blog
454 Bio Unveils Revolutionary Open Source DNA Sequencing Platform 454 Bio, a leader in biotechnological innovation, is excited to announce the launch of a groundbreaking open source DNA sequencing platform. This pioneering initiative is set to …
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January 8 update
Monday, January 08, 2024 in Blog
Proposed January 8 goal 1000 20 Q17, with reads filtered only using the first four bases. How we will get there Quantify incorporation, cleavage, lead, lag, and decay based on fitted experimental results Add images to monitor incorporation and …
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S0592 Sequencing Results
Monday, December 18, 2023 in Blog
Data analysis is finished, and the results are in! Here’s a quick first look at the data from the .html summary output with some key metrics highlighted: Getting an idea of how many reads were loaded compared to how many mapped is important; low …
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Sequencing run S0592 complete! Final step: Analysis
Sunday, December 17, 2023 in Blog
After 16 cycles of incorporation, imaging, and cleaving, sequencing run S0592 is complete! All that’s left to be done is to run through the analysis pipeline. The first step is the Image Pre-Processing Module. The raw sequencing images are fed …
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Setting up Sequencing Run S0592
Sunday, December 17, 2023 in Blog
Today at 454 Bio Jinchun set up our 592nd sequencing run: S0592. This was a standard sequencing run- Jinchun used all of the protocols laid out in Docs to prepare the sequencing reservoir for sequencing on the Mk3 Transformer. To record experimental …